NanoSeal-S is a cold flowable polydimethylsiloxane based root canal sealer with micro silver in chemical form. NanoSeal-S is a polydimethylsiloxane based self curing, antibacterial root canal sealer fortified with nano silver. It is used in conjunction with gutta-percha for effective sealing root canals of permanent teeth. It exhibits an excellent sealing ability and superior radio-opacity. NanoSeal-S exhibits an excellent sealing ability and superior radio-opacity. Nano silver enhances the anti bacterial efficiency and acts as apreservative. Removal of sealant during retreatment NanoSeal-S can be removed by conventional methods. The sealer does not chemically adhere to dentine. Use of heat, gates glidden drills and paeso-reamers are advocated for removal of gutta-percha during post space preparation and retreatment. Excellent flow and superior bio-compatibility Expands by 0.2% to give a tight seal Radiopaque and eugenol free Indications : Root canal sealing using gutta purcha points