R4 is a solution for the cleaning of root canals by irrigation. The presence of chlorhexidine digluconate ensures clean canals, because of its specific action on anaerobic strains in the root-canal flora and endo-periodontal lesions. It is characterized by disinfecting properties with a broad antimicrobial spectrum. It affects the anaerobic strains of bacteria constituting the bacterial flora of the root canals. It shows a long-lasting antibacterial effect and low toxicity. Efficiency equivalent to sodium hypochlorite, but duration of action greater than 48 hours, thanks to its remanent effect INDICATIONS Root-canal irrigation when endodontic re-treatment is required and/or when root-canal treatment requires several sessions.